Funded projects
NIH EB T32 EB025816 (2019-2024)
Training in Computational Neural Engineering
PIs: Stanly, Ting (MPI)
An innovative training program at Georgia Tech and Emory University to train the next generation of researchers at the intersection of computational neuroscience, data science, and clinical neurophysiology.
______________________________________________________________________________________
Emory Synergy/Nexus II for SoM/ECAS collaboration
Mapping the human gait-ome: Automated analysis of individual-specific walking patterns in health & disease
PIs: Ting, Nemenman, Kesar, Berman, McKay
______________________________________________________________________________________
NIH R01 HD90642-06 (2021-2026)
Multi-scale models of proprioceptive encoding to reveal mechanisms of impaired sensorimotor control
MPIs: Ting, Cope, Sawicki
To develop integrated models of muscle spindles proprioceptive afferents and musculotendon dynamics to understand neural contributors to joint hyperresistance disorders across multiple neurological disorders, such as spasticity and hypertonia.
_____________________________________________________________________________________
NSF CMMI 1762211 / 1761679 (2018-2023) (NCE)
Collaborative Research: Enhancing Gait Dynamics via Physical Human-human and Human-Robot Interactions at the Hands
Emory PI: Lena Ting; co-I: Madeleine Hackney
Georgia Tech: PI: Irfan Essa; co-PI: Jun Ueda
To understand how small forces applied to the hand can be used to alter clinically-relevant human gait patterns: Stage 1, the project team will measure interactive human-to-human hand forces and the resulting gait motions that occur during the proposed therapeutic intervention. Stage 2, the project team will develop a model of the motor and cognitive transformations that occurred during Stage 1. They will then embed the models within a novel robotic test-bed to implement physical human-robot interactions at the hands.
_____________________________________________________________________________________
NIH R01 HD46922-10 (2017-2023) (NCE)
Neuromechanical Modeling of Postural Responses: Mechanisms of Balance Impairments in Parkinson's Disease
PI: Lena Ting; co-I's: Erin Buckley, Stewart Factor, Madeleine Hackney, Lucas McKay
To measure and simulate the causal role of increased muscle activity due to rigidity on balance ability
NIH R01 HD090642 (2016-2021)
CRCNS: Collaborative Research: Multi-scale models of muscle spindles for understanding sensorimotor control
PI: Lena Ting; Co-I's: Tim Cope, Ken Campbell (UKentucky)
To develop muscle model based on cross-bridge, musculotendon, and neuron properties that accounts for behaviorally-relevant history-dependent behaviors of sensory encoding in spindles.
NIH R01 NR016151 (2015-2018)
NRI: Collaborative Research: Quadrupedal Human-Assistive Robotic Platform (Q-HARP)
PI: Xianrong Shen (UAlabama); Co-PI's: Sanford Meek, Lena Ting, Cang Ye
Our role is to measure interaction forces between caregivers frail older adults during assisted walking in order to provide design target for an assistive robot.
GT/GSU Center for Advanced Brain Imaging Seed Grant (2016-2017)
Neuroimaging to predict gait rehabilitation outcomes post-stroke
PI: Lena Ting; Co-PI's: Jessica Allen, Michael Borich, Trisha Kesar, Shella Keilholz
To identify whether brain structure and resting state connectivity predict responders and nonresponders to gait rehabilitation.
NSF EFRI 1137229 (2011 -2015, NCE to 2017)
M3C: Partnered Rehabilitative Movement: Cooperative human-robot interaction for motor rehabilitation, learning, and communication
PI: Lena Ting; Co-PI's: Madeleine Hackney, Charlie Kemp, Karen Liu
To develop novel predictive models for motor cooperation based on haptic interaction that forge new paths toward fully automated robots that can physically to enhance, assist, and improve motor skills in humans with varying motor capabilities.
NIH R21 HD075612 (2013 -2015, NCE to 2017)
Mechanisms of improvement in neurorehabilitation of Parkinson's Disease
To investigate improvements in balance following adapted tango rehabilitation are mediated by basal-ganglia versus cerebellar plasticity.
NIH R01 NS053822 (2007-2013)
Neuromechanical Determinants of Muscle Activity in Human Postural Responses
PI: Lena Ting; co-PI's: Steve Wolf
The goal is to experimentally and computationally model spatial and temporal patterns of muscle activity and their functional consequences during human postural control.
NIH R01 HD46922 (2004-2016)
Neuromechanical Modeling of Postural Responses
PI: Lena Ting
The goal is to analyze and model musculoskeletal coordination in the cat hindlimb during balance responses in normal and neurologically impaired animals.
GT Neural Engineering Center Seed Grant (2015-2016)
Measuring and manipulating cortical brain activity for human balance
PI: Lena Ting; co-PI's: Micheal Borich, Minoru Shinohara, Eric Schumacher
To measure changes in electroencephalographic (EEG) event related potentials (ERPs) during perturbation to standing balance, and alter them with noninvasive neural stimuation.
NIH F31 AG081129 (2022-2026)
The effect of aging and cognitive impairment on prefrontal cortical inputs to motor cortical outputs during standing balance control.
Mason (PI)
Co-Mentor with Borich and Kesar
______________________________________________________________________________________
ASEE Fellows Postdoctoral Fellowship
Physiologically inspired, machine learning-based exoskeleton controller to prevent falls
Jakubowski (PI)
Co-Mentor with Sawicki and Young
______________________________________________________________________________________
NIH F31HD107968 (2022-2025)
Individual-specific gait signatures for stroke rehabilitation
Winner (PI)
______________________________________________________________________________________
NIH F32HD105458 (2021-2023)
Correlates of whole-body motion perception during balance perturbations in stroke survivors and their relationship to balance function
Mirdamadi (PI)
______________________________________________________________________________________
NSF GRFP (2020-2023)
Boebinger (PI)
______________________________________________________________________________________
Previous
McCamish Postdoctoral Fellowship (2021-2023)
Muscle coactivation and balance control in older adults with and without Parkinson’s disease
Beck (PI)
______________________________________________________________________________________
NSF GRFP (2019-2022)
Winner (PI)
______________________________________________________________________________________
NIH T32 Translational Neurology (2020-2021)
Correlates of whole-body motion perception during balance perturbations in stroke survivors and their relationship to balance function
Mirdamadi (PI)
Co-Mentor with Borich
______________________________________________________________________________________
AHA Postdoctoral Fellowship (2018-2020)
Cortical connectivity during functional balance reactions in stroke survivors
Palmer (PI)
Co-Mentor with Borich
______________________________________________________________________________________
NIH F32 HD096816 (2019-2021)
Cortical connectivity during functional balance reactions in stroke survivors
Palmer (PI)
Co-Mentor with Borich
______________________________________________________________________________________
Government of Canada, Natural Sciences and Engineering Research Council of Canada
Banting Postdoctoral Fellowship (2018-2020)
How current movement shapes future sensory feedback: A multiscale investigation of how changing muscle mechanics affects muscle spindle sensory feedback and control of standing balance
PI: Brian Horslen
______________________________________________________________________________________
NIH K25HD06276 (2016-2020)
Neural Mechanisms of balance deficit, falls, and freezing of gait in Parkinson's disease
PI: J. Lucas McKay
______________________________________________________________________________________
ACTSI KL2 Mentored Clinical and Translational Research Scholars (MCTRS) (2014-2016)
Reactive Balance to Identify Disease Phenotypes and Predict Falls in Parkinson’s Disease
PI: J. Lucas McKay
______________________________________________________________________________________
NIH F32NS087775 (2015-2017)
Muscle coordination changes affecting impaired balance control post-stroke.
PI: Brian Horslen
______________________________________________________________________________________
NIH F31NS093855 (2015-2018)
Proprioceptive models for control of movement
PI: Kyle Blum
______________________________________________________________________________________
Udall Parkinson's Pilot Grant
PIs: Ting, Borich
Co-Is: McKay, Miocinovic
Coritcal activity underlying impaired reactive and anticipatory postural control in Parkinson's disease.
_________________________________________________________________________________________________________
NIH R01 AG072756-A1 (2021-2026)
Engagement of cortical resources for standing balance control in aging and post-stroke
PIs: Ting, Borich (MPI)
To identify cortical activity signatures of engagement of cortical resources for balance control using EEG during perturbed balance control. (score: 24, 7th %-ile)